Ronan Hughes, of Co Armagh in Northern Ireland, was charged with 39 counts of manslaughter, as well as immigration offences, Essex Police said on Monday.
The 40-year-old is due to appear at Dublin’s High Court on Tuesday.
He was detained on Monday following the execution of a European arrest warrant in Ireland.
The 39 Vietnamese nationals were found in a lorry container parked on an industrial estate in Grays on October 23 last year.
Ten teenagers, including two 15-year-old boys, were among those found dead.
On April 8, Maurice Robinson, 25, of Craigavon in Northern Ireland, pleaded guilty to 39 counts of manslaughter at the Old Bailey in London.
He previously pleaded guilty to conspiracy to assist unlawful immigration and acquiring criminal property at the same court on November 25.
He is due to be sentenced at a later date.
In February, Eamonn Harrison, of Mayobridge, Northern Ireland, was granted permission to appeal against his extradition to the UK under the terms of a European arrest warrant issued by Essex Police.
The 22-year-old is facing 39 manslaughter charges, one of human trafficking and one of assisting unlawful immigration.
A further hearing will be held in Dublin on Thursday May 7, police said.